T1 mapping and T2 mapping at 3T for quantifying the area-at-risk in reperfused STEMI patients

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T1 mapping and T2 mapping at 3T for quantifying the area-at-risk in reperfused STEMI patients

BACKGROUND Whether T1-mapping cardiovascular magnetic resonance (CMR) can accurately quantify the area-at-risk (AAR) as delineated by T2 mapping and assess myocardial salvage at 3T in reperfused ST-segment elevation myocardial infarction (STEMI) patients is not known and was investigated in this study. METHODS 18 STEMI patients underwent CMR at 3T (Siemens Bio-graph mMR) at a median of 5 (4-6...

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Quantification of the area-at-risk by T1 and T2 mapping CMR at 3T

Methods CMR imaging at 3T (Bio-graph mMR, Siemens Healthcare, Erlangen, Germany) was performed in 18 STEMI patients within 10 days of PPCI using T2-mapping and T1-mapping by MOLLI (WIP #699; Siemens Healthcare; UK). Matched short-axis T1 and T2 maps covering the entire left ventricle were analyzed by 2 experienced investigators using 3 analytical methods (in-house macro, ImageJ): manual segment...

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MOLLI T1 mapping versus T2 W-SPAIR at 3T: myocardial area at risk measurements and the influence of microvascular obstruction

Methods CMR imaging was conducted on a Philips 3T Achieva MRI scanner. T2W-weighted spectral attenuated inversion recovery (T2WW-SPAIR), modified look-locker inversion recovery (MOLLI) T1 mapping and late gadolinium enhancement (LGE) sequences were applied as short axis stacks in 10 healthy volunteers and 62 STEMI patients. Receiver operator characteristic (ROC) analysis was applied to calculat...

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Robust myocardial T2 and T2* mapping at 3T

PURPOSE Intramyocardial hemorrhage and area at risk are both prognostic markers in acute myocardial infarction (AMI). Myocardial T2 and T2 * mapping have been used to detect such tissue changes at 1.5T but these techniques are challenging at 3.0T due to additional susceptibility variation. We studied T2 and T2 * myocardial mapping techniques at 3.0T on a system employing B1 shimming and compare...

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Segment-based myocardial T1 and T2 mapping at 3T: feasibility and normal values

Methods Sixty healthy volunteers (30 males / 30 females, 20 in each age group: 20-39 years, 40-59 years, 60-80 years) underwent T1 and T2 mapping of the left ventricle in 3 short axis slices. For T2 maps, 3 single shot steady state free precession (SSFP) images with different T2 preparation times (0, 24, 55ms) were acquired (TE 1.0 ms, TR 2.4 ms, voxel 1.9 x 1.9x6 mm). For T1 maps, Modified Loo...

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ژورنال

عنوان ژورنال: Journal of Cardiovascular Magnetic Resonance

سال: 2015

ISSN: 1532-429X

DOI: 10.1186/s12968-015-0173-6